POL.it POL.it banner POL.it banner POL.it banner POL.it banner logo feedback POL.it banner
POL.it banner POL.it banner POL.it banner POL.it banner POL.it banner POL.it banner POL.it banner
POL.it banner POL.it banner POL.it banner POL.it banner POL.it banner POL.it banner POL.it banner

spazio bianco

NORADRENALINA E DEPRESSIONE

Ruolo del sistema noradrenergico nella fisiopatologia della depressione e nel meccanismo d'azione degli antidepressivi

Nicoletta Brunello1 e Joan M.C. Blom1,2

 

 

Bibliografia

Brunello N., Racagni G. (1998) Rationale for the development of noradrenaline reuptake inhibitors. Human Psychopharmacology, 13: S13-S19.

Delgado PL., Miller HL., Salomon RM., Licinio J., et al., (1993) Monoamines and the mechanism of antidepressant action: effects of catecholamine depletion on mood of patients treated with antidepressants. Psychopharmacology Bulletin, 29: 389-396.

Delgado PL., Moreno FA., Potter R., Gelenberg AJ. (1997) Norepinephrine and serotonin in antidepressant action: evidence from neurotransmitter depletion studies. In Briley M. (ed), Antidepressant Therapy at the Dawn of the Third Millennium. London: Martin Dunitz Ltd; pp 141-163.

Dostert P., Strolin-Benedetti S., Poggesi I. (1997) Review of the pharmacokinetics and metabolism of reboxetine, a selective noradrenaline reuptake inhibitor. Eur. Neuropsychopharmacology, 7: 23-35.

Dubini A., Bosc M., Polin V. (1997) Noradrenaline-selective versus serotonin-selective antidepressant therapy: differential effect on social functioning. J Psychopharmacol 11: S17-S23.

Extein J., Tallman J., Smith CC:, Goodwin FK. (1979) Changes in lymphocyte beta-adrenergic receptors in depression and mania. Psychiatry Research 1: 191-197.

Karege F., Bovier P., Gaillard JM., Tissot R. (1989) The heterogeneity of 3-metoxy-4-hydroxyphenylglycol levels among depressed patients. Acta Psych. Scandinavica 80: 499-504.

Leonard BE. (1986) Neurotransmitter receptors, endocrine responses and the biological substrates of depression: a review. Human Psychopharmacology. 1: 3-18.

Leonard BE. (1997) The role of noradrenaline in depression: a review. J Psychopharmacol 11: 39-47.

Melloni P., Carniel G., Della Torre A., et al., (1984) Potential antidepressant agents. Alpha-aryloxy-benxyl derivatives of ethanolamine and morpholine. Eur. J. Med. Chemistry 19: 235-242.

Miller HL., Delgado PL., Salomon RM. et al., (1996) Clinical and biochemical effects of catecholamine depletion on antidepressant-induced remission of depression. Arch. Gen. Psychiatry 53:, 117-128

Montgomery SA. (1997) Reboxetine: additional benefits to the depressed patient. J Psychopharmacol 11: 9-15.

Mucci M. (1997) Reboxetine: a review of antidepressant tolerability. J Psychopharmacol 11: 33-37.

Nutt DJ. (1997) Noradrenaline in depression: Half a century of progress. Journal of Psychopharmacology 11: S3.

Ordway GA, Stockmeier CA, Cason GW, Klimek V. (1997) Pharmacology and distribution of norepinephrine transporters in the human locus coeruleus and Raphe nuclei. J Neurosci; 17: 1710-1719.

Riva M., Brunello N., Rovescalli AC., Galimberti R., Carfagna N., Carminati P., Pozzi O., Ricciardi S., Roncucci R., Rossi A., Racagni G. (1989) Effect of reboxetine, a new antidepressant drug, on the central noradrenergic system: behavioural and biochemical studies. J Drug Development 1: 243-253.

Schatzberg AF, Schildkraut JJ. (1995) Recent studies on norepinephrine systems in mood disorders. In Psychopharmacology: the Fourth Generation of Progress. Bloom FE. and Kupfer DJ. (eds) Raven Press, New York, pp. 911-920.

Schildkraut JJ, (1965) The catecholamine hypothesis of affective disorders: a review of supporting evidence. Am. J. Psychiat. 122:509-522.

Siever LJ., Uhde TW., Jimerson DC. et al. (1983) Clinical studies of monoamine receptors in the affective disorders and receptor changes with antidepressant treatment. Prog Neuro-Psychopharmacol Biol Psychiatr, 7: 249-261.

 

1Dipartimento di Scienze Farmaceutiche, Università degli Studi di Modena e Reggio Emilia

2 I.R.C.C.S. San Giovanni di Dio-Fatebenefratelli, Brescia

spazio bianco

RED CRAB DESIGN

spazio bianco

Priory lodge LTD

Click Here!